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Angiotensin Converting Enzyme

The Angiotensin Converting Enzyme (ACE) blood test is a diagnostic procedure used to assess the level of ACE in the bloodstream, an enzyme integral to the renin-angiotensin system that regulates blood pressure. This test is particularly useful in diagnosing and monitoring conditions like sarcoidosis, a disease marked by the formation of granulomas, which are clusters of inflammatory cells. The test involves drawing a blood sample, which is then analyzed in a laboratory to determine ACE levels. Elevated ACE levels can indicate conditions such as sarcoidosis, Addison's disease, and certain lung diseases, while lower levels may suggest chronic liver or kidney disease. The test is generally safe, with minimal risks such as slight bruising at the puncture site. Accurate interpretation of results requires considering the patient's overall clinical picture and other diagnostic findings. The ACE test is a crucial tool for healthcare providers in managing and understanding inflammatory and granulomatous diseases.

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Price of test:£103

The lowest price from the last 30 days: £103

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Awaiting result:

One day

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Collect material:

Urine

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Prepare:

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Purpose of the test

The Angiotensin Converting Enzyme (ACE) blood test measures ACE levels, crucial in regulating blood pressure. It aids in diagnosing and monitoring conditions like sarcoidosis and other inflammatory diseases. Here's a brief overview:

- Test Procedure: Involves drawing blood, with steps including preparation, blood collection, and sample processing.
- Normal Results: Typically less than 40 micrograms per liter for adults.
- Abnormal Results:
- High levels may indicate sarcoidosis, lung diseases, or thyroid issues.
- Low levels could suggest liver or kidney problems.
- Risks: Minimal, with slight bruising or soreness possible.

Who Should Get Tested

The ACE blood test is crucial for diagnosing and monitoring conditions involving inflammation and granulomatous diseases. It measures angiotensin-converting enzyme levels, providing insights into the body's physiological state. Key points include:

- Higher ACE Levels: May indicate sarcoidosis, Addison's disease, or lung diseases like asthma.
- Lower ACE Levels: Could suggest chronic liver disease or hypothyroidism.
- Procedure: Involves drawing blood, with minimal risks such as bruising.
- Interpretation: Elevated levels, combined with other findings, suggest sarcoidosis.

This test aids in assessing various conditions, primarily sarcoidosis.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Preparing for Urinalysis Test
Buy container
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Buy sterile, disposable urine containers from pharmacies.

You can also buy a container from a diagnostic centre but the price will be higher. Container is not included in the price of the tests.
Time of day
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Ideally, collect the first urine in the morning after an 8-hour overnight rest or at least 4 hours after the last urination to prevent functional proteinuria.
Mid-stream Sample
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Collect the urine mid-stream, not at the beginning or end of urination, to avoid contamination. The sample volume should be 20 to 100 milliliters, depending on the container's size.
Hygiene
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Wash the area around the urethra with warm water, without using any cleaning or disinfecting products.
Fasting
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Do not eat or drink for 12 hours before collecting the urine sample. If necessary, you can drink one glass of clean, unflavoured water during this time.
Physical activity
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Avoid intense physical activity before providing a urine sample, as it can lead to an increase in protein and ketone levels in urine.
Menstrual period
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Women should avoid providing a urine sample during the menstrual period or within two days of its completion, as this can affect the test results due to the presence of red blood cells and epithelial cells in the urine.
Sexual activity
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Abstain from sexual activity before providing a urine sample.
Deliver sample
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Take the sample(s) to the sampling point on the same day. Storage: Keep the samples at refrigerated temperature (+2...+8°C) until they are taken to the sampling point.
Interpreting Test Results

Understanding test results for the Angiotensin Converting Enzyme (ACE) blood test is crucial for diagnosing and monitoring conditions like sarcoidosis. Here's a brief overview:

- Normal Range: Typically less than 40 micrograms per liter for adults, but varies by lab.
- Elevated Levels: May indicate sarcoidosis, lung diseases, or thyroid disorders.
- Lower Levels: Could suggest chronic liver or kidney disease, or hypothyroidism.

Interpreting results requires considering clinical symptoms and other diagnostic findings. Always consult with a healthcare provider for accurate assessment.

Price of test:£103

The lowest price from the last 30 days: £103

AI-Powered Insights and Expert Validation
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