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Anti CCP Antibodies

Anti CCP Antibodies

The Anti-Cyclic Citrullinated Peptide (Anti-CCP) antibody test is a vital diagnostic tool for identifying rheumatoid arthritis (RA), an autoimmune disorder characterized by joint inflammation and pain. This blood test detects CCP antibodies, proteins produced in response to citrullinated peptides found in the joints of RA patients. Conducted via an enzyme-linked immunosorbent assay (ELISA), the test involves drawing a blood sample, separating the serum, and analyzing it for CCP antibodies. A positive result suggests RA, although it can also occur in other autoimmune conditions like lupus or Sjögren syndrome. The test boasts high specificity for RA, aiding in early diagnosis, assessing disease severity, and monitoring treatment efficacy. While generally safe, the test requires caution with biotin supplements, which can affect results. Overall, the Anti-CCP antibody test is a crucial component in the comprehensive evaluation of RA, guiding healthcare providers in diagnosis and treatment planning.

Price of test:£59

The lowest price from the last 30 days: £59

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Anti-CCP antibody test is a vital diagnostic tool for rheumatoid arthritis (RA). It measures CCP antibodies in the blood to confirm or rule out RA. The test involves:

- Blood Collection: A sample is drawn from a vein.
- Serum Separation: Serum is isolated from the blood.
- ELISA Procedure: Serum is tested for CCP antibodies.

A positive result suggests RA but must be interpreted with clinical findings. The test is highly specific, aiding in diagnosis, assessing disease severity, and monitoring treatment. Precautions include avoiding biotin supplements before testing.

Who Should Get Tested

The Anti-Cyclic Citrullinated Peptide (Anti-CCP) antibody test is essential for diagnosing rheumatoid arthritis (RA). It involves a blood draw to measure CCP antibodies, aiding in RA confirmation. Key points include:

- Diagnosis: Helps identify RA, especially in early stages.
- Disease Severity: High CCP levels may indicate severe RA.
- Monitoring: Assesses treatment effectiveness.

Precautions involve avoiding biotin supplements before testing. While a positive result suggests RA, it must be interpreted with clinical findings. The test is a valuable tool for accurate diagnosis and treatment planning.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for making informed healthcare decisions. The Anti-CCP antibody test is a key diagnostic tool for rheumatoid arthritis (RA). Here's what the results mean:

- Positive Result: Indicates the presence of CCP antibodies, suggesting RA, especially with clinical symptoms. However, other autoimmune conditions can also yield positive results.
- Specificity: High specificity for RA; about 70% of RA patients test positive.
- Clinical Utility: Useful for diagnosing RA, assessing disease severity, and monitoring treatment effectiveness.
- Considerations: Biotin supplements may affect results; inform your healthcare provider about any supplements or medications.

Price of test:£59

The lowest price from the last 30 days: £59

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