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Anti Nuclear Ab

Anti Nuclear Ab

The Antinuclear Antibody (ANA) test is a vital diagnostic procedure used to detect antinuclear antibodies in the blood, which can indicate the presence of autoimmune disorders. Autoimmune diseases occur when the immune system mistakenly attacks the body's own tissues, causing symptoms like joint pain and fatigue. The ANA test involves drawing a blood sample, which is then analyzed in a laboratory using the indirect immunofluorescent ANA (IIF-ANA) method. This technique uses fluorescent dyes to visualize antibody binding patterns on human epithelial cells, helping to interpret the results. A positive ANA result suggests the presence of autoantibodies but does not confirm an autoimmune disease, as healthy individuals can also test positive. The test is commonly used to evaluate conditions such as lupus, scleroderma, and Sjögren’s syndrome. While generally safe, the procedure carries minimal risks like bleeding or infection. Positive results often require further testing to identify specific autoimmune disorders.

Price of test:£59

The lowest price from the last 30 days: £59

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Antinuclear Antibody (ANA) test is essential for diagnosing autoimmune disorders by detecting autoantibodies in the blood. It helps identify individuals at risk of conditions like lupus and Sjögren’s syndrome. The test involves:

- Drawing a blood sample from a vein.
- Analyzing the sample using the indirect immunofluorescent ANA (IIF-ANA) method.

Results are reported as titer levels and fluorescence patterns, aiding in diagnosis. A positive result requires further testing, as it doesn't confirm disease presence. The test is safe, with minimal risks like:

- Excessive bleeding
- Fainting
- Hematoma
- Infection

Follow-up tests may include specific autoantibody assessments.

Who Should Get Tested

The Antinuclear Antibody (ANA) test is essential for diagnosing autoimmune disorders by detecting autoantibodies in the blood. It helps identify individuals at risk of conditions like lupus and Sjögren’s syndrome. The test involves:

- Drawing a blood sample
- Analyzing it under a microscope with ultraviolet light

Results are reported as titer levels and fluorescence patterns, aiding in diagnosis. A positive result requires further testing, as it doesn't confirm an autoimmune disease. Conditions linked to positive results include:

- Autoimmune diseases
- Certain infections
- Some cancers
- Medications
- Aging

The test is generally safe, with minimal risks.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is crucial for interpreting the Antinuclear Antibody (ANA) test. Here's a brief guide:

- Titer Levels: Results are reported in titers, such as 1:40 or 1:160. Higher titers may indicate a greater likelihood of autoimmune activity.
- Fluorescence Patterns: Patterns like homogeneous or speckled provide clues about potential autoimmune disorders.
- Negative Results: Suggest no autoantibodies detected, reducing the likelihood of an autoimmune disorder.
- Positive Results: Require further testing, as they don't confirm a disease but indicate potential risk.
- Considerations: Age, medications, and infections can influence results.

Price of test:£59

The lowest price from the last 30 days: £59

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