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Aspergillus fumigatus IgG

Aspergillus fumigatus IgG

The Aspergillus fumigatus IgG test is a specialized laboratory assay used to detect antibodies against the fungus *Aspergillus fumigatus* in a patient's serum. This test is crucial for diagnosing and monitoring conditions like allergic bronchopulmonary aspergillosis (ABPA), chronic pulmonary aspergillosis (CPA), and hypersensitivity pneumonitis (HP). It employs a Fluorescence Enzyme Immunoassay (FEIA) to measure antibody levels, providing insights into a patient's sensitization to the fungus. A positive result suggests exposure and potential sensitization, aiding in the diagnosis of related conditions. However, the test has limitations, such as varying specificity and sensitivity, and is not suitable for diagnosing invasive pulmonary aspergillosis (IPA) in immunocompromised patients. Interpretation requires a comprehensive approach, considering clinical, radiological, and exposure history. Despite its limitations, the test is a valuable tool in managing *A. fumigatus*-related diseases, guiding treatment decisions, and implementing antigen avoidance strategies for conditions like HP.

Price of test:£34

The lowest price from the last 30 days: £34

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Aspergillus fumigatus IgG test is crucial for diagnosing and monitoring conditions related to *A. fumigatus*. It measures specific antibodies in serum, aiding in the diagnosis of:

- ABPA: Indicates sensitization in asthma or cystic fibrosis patients.
- CPA: Supports diagnosis alongside clinical and radiological evidence.
- HP: Assists in identifying antigen-induced hypersensitivity.

The test uses a Fluorescence Enzyme Immunoassay, with results interpreted as negative, equivocal, or positive. While valuable, it requires careful consideration of clinical context and has limitations, particularly in severely immunocompromised patients.

Who Should Get Tested

The Aspergillus fumigatus IgG test is crucial for diagnosing conditions like ABPA, CPA, and HP. It measures specific antibodies against *A. fumigatus* in serum, aiding in identifying sensitization to the fungus. Key points include:

- ABPA: Affects asthma or cystic fibrosis patients; high IgG levels indicate sensitization.
- CPA: Associated with chronic lung diseases; IgG levels support diagnosis but aren't always reliable.
- HP: Triggered by environmental exposure; positive IgG indicates sensitization.

The test uses a Fluorescence Enzyme Immunoassay, with results interpreted alongside clinical findings for accurate diagnosis.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the Aspergillus fumigatus IgG test is crucial for accurate diagnosis and management of related conditions. Here's a brief overview:

- Negative Results: No significant antibodies detected; does not rule out infection, especially in immunocompromised patients.
- Equivocal Results: Uncertain presence of antibodies; further testing may be needed.
- Positive Results: Indicates sensitization to *A. fumigatus*; supports diagnosis of conditions like ABPA or HP, but must be considered with clinical and radiological data.

Understanding these results helps guide treatment and management strategies effectively.

Price of test:£34

The lowest price from the last 30 days: £34

AI-Powered Insights and Expert Validation

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