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Brucella agglutinins

The Brucella IgG antibody test is a serological examination designed to detect IgG antibodies against Brucella bacteria in blood serum, aiding in the diagnosis and monitoring of brucellosis. This systemic bacterial infection is caused by Brucella species such as Brucella abortus, Brucella melitensis, and Brucella suis, often contracted through contact with infected animals or consumption of contaminated animal products. High-risk groups include farmers, veterinarians, and slaughterhouse workers. The test involves drawing a blood sample, separating the serum, and using an Enzyme-Linked Immunosorbent Assay (ELISA) to identify antibodies. Results are categorized as positive, negative, or equivocal, with positive results indicating exposure to Brucella. However, IgG antibodies can persist long after infection, necessitating consideration of clinical symptoms and history. While the test is a valuable diagnostic tool, it has limitations, including potential cross-reactivity and false positives, requiring confirmation through additional testing for accurate diagnosis and treatment planning.

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Price of test:£68

The lowest price from the last 30 days: £68

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Brucella IgG antibody test is essential for diagnosing brucellosis by detecting IgG antibodies in blood serum. It is particularly important for individuals at high risk, such as farmers and veterinarians. The test involves:

- Collecting a blood sample
- Using ELISA methodology
- Incubating serum with Brucella antigens

Results are interpreted as positive, negative, or equivocal, considering clinical symptoms. Limitations include:

- Cross-reactivity with other species
- Potential false positives and negatives

Despite these, it remains a vital diagnostic tool.

Who Should Get Tested

The Brucella IgG antibody test is essential for diagnosing brucellosis, especially in high-risk groups. Individuals who should be tested include:

- Slaughterhouse workers
- Farmers
- Veterinarians
- Those handling animals or animal products

The test involves a blood sample analyzed using ELISA to detect IgG antibodies. Results can be positive, negative, or equivocal, requiring careful interpretation alongside clinical symptoms. Limitations include potential cross-reactivity and false results. Despite these, the test is vital for accurate diagnosis and management of brucellosis.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results is essential for accurate diagnosis and treatment. The Brucella IgG antibody test detects IgG antibodies against Brucella bacteria, aiding in diagnosing brucellosis. Key points include:

- Positive Result: Indicates exposure to Brucella; IgG antibodies may persist long after infection.
- Negative Result: Suggests no exposure, but early-stage infections may not be detected.
- Equivocal Result: Requires further testing for confirmation.

Consider cross-reactivity and potential false positives or negatives. Always interpret results alongside clinical symptoms and patient history for a comprehensive evaluation.

Price of test:£68

The lowest price from the last 30 days: £68

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