Brucella IgG

The Brucella IgM antibody test is a vital diagnostic tool for detecting IgM antibodies against Brucella bacteria in the blood, crucial for diagnosing brucellosis. This bacterial infection, often contracted through contact with infected animals or consumption of contaminated products, presents with symptoms like fever, fatigue, and joint pain. The test employs an Enzyme-Linked Immunosorbent Assay (ELISA) to identify these antibodies, using a blood sample to detect recent or active infections. Results are categorized as positive, negative, or equivocal, with positive results indicating recent exposure, though not necessarily active infection. Negative results may require retesting, while equivocal outcomes often need further confirmation through bacterial agglutination. Despite its utility, the test has limitations, such as potential cross-reactivity and inability to differentiate between Brucella species. Confirmatory testing is recommended for positive or equivocal results. Widely available in clinical labs, the test is essential for guiding treatment and ensuring accurate diagnosis of brucellosis.

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Price of test:£34

The lowest price from the last 30 days: £34

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Brucella IgM antibody test is essential for diagnosing brucellosis, a bacterial infection. It detects IgM antibodies in blood, indicating recent exposure to Brucella bacteria. The test uses ELISA, a sensitive method involving:

- Sample Collection: Blood is drawn and placed in a serum separator tube.
- Serum Separation: Centrifugation separates serum from blood components.
- Antibody Detection: Serum is tested for IgM antibodies using Brucella antigens.
- Result Interpretation: Results can be positive, negative, or equivocal.

Positive results suggest recent infection, but further testing is needed for confirmation.

Who Should Get Tested

The Brucella IgM antibody test is essential for diagnosing brucellosis, a bacterial infection from Brucella species. It detects IgM antibodies in the blood, crucial for confirming infection and guiding treatment. Key points include:

- Sample Collection: Blood is drawn and serum separated.
- Antibody Detection: ELISA method identifies IgM antibodies.
- Result Interpretation: Positive suggests recent exposure; negative doesn't rule out infection; equivocal needs further testing.

Limitations involve cross-reactivity and false positives. Confirmatory testing, like bacterial agglutination, ensures accurate diagnosis. Understanding these aspects aids effective brucellosis management.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results is essential for accurate diagnosis and treatment. Here's a brief guide:

- Positive Results: Indicate recent exposure to Brucella bacteria. However, it may not confirm active infection due to potential cross-reactivity with other bacteria.

- Negative Results: Do not rule out brucellosis, as antibodies might not be detectable early. A repeat test after three weeks is advisable.

- Equivocal Results: Require further testing, like bacterial agglutination, to confirm Brucella antibodies and rule out false positives.

Understanding these outcomes helps in managing brucellosis effectively.

Price of test:£34

The lowest price from the last 30 days: £34

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