Cacao IgE

The carbamazepine test is an essential diagnostic tool used to measure the levels of carbamazepine, a medication primarily prescribed for epilepsy and certain seizure types. This test ensures that drug levels remain within a therapeutic range, optimizing treatment efficacy while preventing toxicity. Carbamazepine is effective for partial and generalized tonic-clonic seizures but not for absence or myoclonic seizures. The test involves a simple blood draw, with the sample analyzed to determine carbamazepine concentration. Physicians use this test to monitor treatment effectiveness, adjust dosages, and check for adverse effects. It is crucial for patients to inform their healthcare provider about any other medications they are taking, as these can affect test results. Regular monitoring helps manage therapy, ensuring compliance and preventing toxicity. Additionally, pharmacogenetic testing for the HLA-B*15:02 allele is recommended for patients at risk of hypersensitivity reactions, such as Stevens-Johnson syndrome, particularly in individuals of Asian descent.

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Price of test:£34

The lowest price from the last 30 days: £34

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The carbamazepine test is essential for managing epilepsy treatment, ensuring drug levels remain therapeutic, and preventing toxicity. Key objectives include:

- Monitoring Drug Levels: Ensures effectiveness and safety by keeping levels within 4.0 to 12.0 μg/mL.
- Adjusting Dosage: Guides necessary changes to maintain optimal levels.
- Ensuring Compliance: Confirms adherence to prescribed regimens.
- Identifying Risks: Detects potential hypersensitivity, especially in patients with HLA-B*15:02 allele.
- Preventing Adverse Effects: Helps avoid toxicity and serious reactions like Stevens-Johnson syndrome.

Who Should Get Tested

The carbamazepine test is crucial for patients on carbamazepine therapy, primarily used to treat epilepsy. It ensures drug levels remain within the therapeutic range, preventing toxicity. Key points include:

- Who Needs Testing: Patients starting carbamazepine, those experiencing side effects, or showing signs of ineffective treatment.
- Monitoring: Regular testing helps adjust dosages and ensures compliance.
- Risks: Patients of Asian descent should be tested for HLA-B*15:02 to avoid severe reactions.
- Procedure: A simple blood test with no specific prerequisites, but inform the physician about other medications.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results for the carbamazepine test is crucial for effective epilepsy management. Key points include:

- Therapeutic Range: Ensures drug levels are between 4.0 to 12.0 μg/mL.
- Low Levels: May indicate ineffective treatment.
- High Levels: Risk of toxicity.
- Dose Adjustments: Necessary for maintaining optimal levels.
- Pharmacogenetics: Testing for HLA-B*15:02 allele to prevent severe reactions.
- Regular Monitoring: Ensures compliance and effective metabolism.
- Risks: Includes potential for bleeding or infection during blood draw.

Price of test:£34

The lowest price from the last 30 days: £34

AI-Powered Insights and Expert Validation
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