Chestnut IgE

The Chestnut IgG test is a diagnostic tool designed to detect immunoglobulin G (IgG) antibodies specific to chestnut allergens in a patient's serum. This test is primarily used in clinical settings to evaluate the immune response to chestnut allergens, aiding in the diagnosis and management of allergies. While the clinical utility of food-specific IgG tests, including the Chestnut IgG test, is not fully established, they can be beneficial in certain clinical scenarios. These tests help in selecting foods for diet elimination and challenge in patients with food-related complaints. The presence of food-specific IgG indicates immunologic sensitization but does not confirm a food allergy. The test employs an enzyme immunoassay (FEIA) method, requiring a serum sample for analysis. Results are expressed in micrograms per milliliter (mcg/mL) and should be interpreted by healthcare providers familiar with the test's limitations. The Chestnut IgG test can guide dietary interventions but should not be the sole diagnostic tool for food allergies.

Price of test:£34

The lowest price from the last 30 days: £34

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Chestnut IgG test is a diagnostic tool used to detect IgG antibodies specific to chestnut allergens in serum. It aids in assessing immune responses, though its clinical utility is not fully established. Key points include:

- Methodology: Uses enzyme immunoassay (FEIA) for IgG concentration.
- Specimen Requirements: Serum sample, 0.5 mL minimum.
- Handling: Store refrigerated, stable for 3 days.
- Turnaround: Results in 3 business days.
- Interpretation: Results in mcg/mL, indicating sensitization, not allergy.
- Limitations: Not definitive for allergies; requires cautious interpretation.

Who Should Get Tested

The Chestnut IgE test is essential for diagnosing chestnut allergies, specifically Castanea sativa. It identifies specific IgE antibodies, aiding in allergy management and confirming sensitization before immunotherapy. The test uses the ImmunoCAP FEIA method, involving:

- Specimen Collection: Serum sample in a gel or red top tube.
- Specimen Preparation: Centrifuge, aliquot, and refrigerate or freeze.
- Testing: Serum added to allergen-coated phase, followed by enzyme-labeled anti-IgE.

Results are classified from Class 0 (Negative) to Class 6 (Very High Positive). It's crucial for diagnosing allergies, confirming sensitization, and monitoring treatment. Interpretation considers clinical context to avoid false positives.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the Chestnut IgG test involves several key considerations:

- Clinical Utility: This test helps identify immunologic sensitization to chestnut allergens but does not confirm an allergy. It should be used alongside other diagnostic methods.

- Methodology: Utilizes enzyme immunoassay (FEIA) to measure IgG concentrations, ensuring standardized results.

- Specimen Requirements: Requires a serum sample, preferably in a serum separator tube, with specific volume guidelines.

- Turnaround Time: Results are typically available within 3 business days.

- Interpretation: Results are expressed in mcg/mL, indicating IgG concentration levels.

- Limitations: Presence of IgG does not confirm an allergy; further testing may be needed.

Price of test:£34

The lowest price from the last 30 days: £34

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