Cobalt - Urine

The Cobalt - Blood test is a vital laboratory examination designed to measure cobalt levels in the blood, crucial for diagnosing and managing cobalt exposure-related conditions. Cobalt, while essential in various industries, can cause toxicity if exposure is excessive, leading to symptoms like cardiomyopathy and pulmonary issues. This test is particularly important for individuals in industries such as mining and alloy production, where cobalt exposure is common. It involves collecting a whole blood specimen in a royal blue top (EDTA) Vacutainer tube, with a minimum volume of 0.5 mL required. Utilizing Inductively Coupled Plasma-Mass Spectrometry (ICP-MS), the test offers precise cobalt level measurements. Elevated results suggest possible exposure, with interpretation considering exposure sources, such as orthopedic implants. Special handling instructions are crucial to avoid contamination, and the test is not suitable for assessing vitamin B12 activity. Its clinical applications include monitoring occupational exposure, diagnosing toxic ingestion, and evaluating metal-on-metal implant wear.

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Price of test:£97

The lowest price from the last 30 days: £97

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Awaiting result:

One day

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Collect material:

Urine

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Prepare:

Learn more
Purpose of the test

The Cobalt - Blood test is a vital diagnostic tool for measuring cobalt levels in the blood, crucial for identifying exposure and potential toxicity. It serves several key purposes:

- Occupational Exposure: Essential for workers in industries like mining and alloy production, ensuring safety by monitoring cobalt levels.
- Toxic Ingestion: Detects cobalt toxicity symptoms such as cardiomyopathy and pulmonary fibrosis, enabling timely intervention.
- Metal-on-Metal Implants: Monitors cobalt levels in patients with such implants, indicating potential prosthetic wear.

Accurate results depend on proper specimen collection and handling, using ICP-MS for precise analysis.

Who Should Get Tested

The cobalt urine test is essential for monitoring cobalt exposure in clinical and occupational settings. Key groups needing testing include:

- Industrial Workers: Those in hard alloys, glass, and pigment manufacturing are at risk.
- Patients with Prosthetic Implants: Especially those with metallic hip replacements, to detect implant wear.
- Environmental Exposure: Individuals in areas with potential cobalt contamination.

Proper specimen collection and handling are crucial for accurate results. Elevated cobalt levels can indicate exposure or implant wear, necessitating protective measures or medical intervention.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Preparing for Urinalysis Test
Buy container
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Buy sterile, disposable urine containers from pharmacies.

You can also buy a container from a diagnostic centre but the price will be higher. Container is not included in the price of the tests.
Time of day
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Ideally, collect the first urine in the morning after an 8-hour overnight rest or at least 4 hours after the last urination to prevent functional proteinuria.
Mid-stream Sample
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Collect the urine mid-stream, not at the beginning or end of urination, to avoid contamination. The sample volume should be 20 to 100 milliliters, depending on the container's size.
Hygiene
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Wash the area around the urethra with warm water, without using any cleaning or disinfecting products.
Fasting
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Do not eat or drink for 12 hours before collecting the urine sample. If necessary, you can drink one glass of clean, unflavoured water during this time.
Physical activity
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Avoid intense physical activity before providing a urine sample, as it can lead to an increase in protein and ketone levels in urine.
Menstrual period
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Women should avoid providing a urine sample during the menstrual period or within two days of its completion, as this can affect the test results due to the presence of red blood cells and epithelial cells in the urine.
Sexual activity
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Abstain from sexual activity before providing a urine sample.
Deliver sample
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Take the sample(s) to the sampling point on the same day. Storage: Keep the samples at refrigerated temperature (+2...+8°C) until they are taken to the sampling point.
Interpreting Test Results

Understanding test results from the Cobalt - Blood test is crucial for diagnosing and managing cobalt exposure. Here's a brief guide:

- Elevated Levels: Indicate potential cobalt exposure. Contextual interpretation is essential, especially for those with orthopedic implants.
- Occupational Exposure: Regular testing is advised for workers in cobalt-related industries.
- Toxic Ingestion: Early detection is vital for preventing long-term health issues.
- Implant Monitoring: Elevated levels may suggest prosthetic wear, requiring further evaluation.

Accurate interpretation aids in effective treatment and management of cobalt-related conditions.

Price of test:£97

The lowest price from the last 30 days: £97

AI-Powered Insights and Expert Validation
Advanced AI Interpretation
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