The direct bilirubin test is an essential diagnostic procedure used to evaluate liver function by measuring the amount of conjugated bilirubin in the blood or urine. Bilirubin, a yellow pigment, is produced during the breakdown of red blood cells and is processed by the liver to become water-soluble for excretion. This test is crucial for diagnosing liver and bile duct disorders, such as hepatitis, cirrhosis, and bile duct obstructions, where the liver's ability to conjugate bilirubin is compromised. The test specifically measures the conjugated form of bilirubin, distinct from the unconjugated form, and is performed by analyzing a blood sample. Results are expressed in milligrams per deciliter, with normal levels ranging from 0 to 0.3 mg/dL. Elevated levels may indicate liver diseases, bile duct obstructions, or rare liver conditions. The direct bilirubin test is often part of a comprehensive liver panel, providing valuable insights for diagnosing and managing liver-related health issues.
The direct bilirubin test is an essential diagnostic procedure used to evaluate liver function by measuring the amount of conjugated bilirubin in the blood or urine. Bilirubin, a yellow pigment, is produced during the breakdown of red blood cells and is processed by the liver to become water-soluble for excretion. This test is crucial for diagnosing liver and bile duct disorders, such as hepatitis, cirrhosis, and bile duct obstructions, where the liver's ability to conjugate bilirubin is compromised. The test specifically measures the conjugated form of bilirubin, distinct from the unconjugated form, and is performed by analyzing a blood sample. Results are expressed in milligrams per deciliter, with normal levels ranging from 0 to 0.3 mg/dL. Elevated levels may indicate liver diseases, bile duct obstructions, or rare liver conditions. The direct bilirubin test is often part of a comprehensive liver panel, providing valuable insights for diagnosing and managing liver-related health issues.
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The direct bilirubin test is essential for evaluating liver function and diagnosing liver and bile duct disorders. It measures conjugated bilirubin, processed by the liver for excretion. Elevated levels can indicate:
- Liver diseases: hepatitis, cirrhosis
- Bile duct obstructions: gallstones, tumors
- Cholestatic drug reactions
- Rare syndromes: Dubin-Johnson, Rotor
Symptoms of elevated bilirubin include jaundice, dark urine, and abdominal pain. The test uses serum or plasma, with results typically available within a day. Proper specimen handling is crucial to avoid rejection.
In regions where dengue fever is endemic, testing for Dengue IgG and IgM antibodies is essential. This test helps identify past or current infections and distinguishes between primary and secondary infections, which can have different clinical outcomes.
- IgG Antibodies: Indicate past exposure; persist long-term.
- IgM Antibodies: Indicate recent infection; appear early.
Testing involves collecting acute and convalescent sera to compare antibody levels. This helps determine infection type. Specimens must be handled carefully to ensure accuracy. ELISA is used for detection, but cross-reactivity with other flaviviruses can occur.
Understanding test results is essential for interpreting the direct bilirubin test, a key diagnostic tool for liver function. This test measures conjugated bilirubin, processed by the liver for excretion. Elevated levels can indicate:
- Liver diseases: Hepatitis, cirrhosis
- Bile duct obstructions: Gallstones, tumors
- Drug reactions: Affecting bile flow
Symptoms of elevated bilirubin include jaundice and dark urine. The test is part of a liver panel, requiring serum or plasma, with results typically available within a day. Proper specimen handling ensures accurate results.
The lowest price from the last 30 days: £115
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