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Gastric Parietal Cell Abs

Gastric Parietal Cell Abs

The Grapefruit IgG test is a laboratory examination that measures immunoglobulin G (IgG) antibodies specific to grapefruit in a patient's serum. IgG antibodies are part of the immune system, providing long-term immunity. The presence of grapefruit-specific IgG indicates immunologic sensitization but does not confirm a food allergy. The test's clinical utility is limited and primarily used in special situations to guide dietary evaluations through elimination and challenge methods. Conducted via enzyme immunoassay, the test requires a blood sample, typically drawn in a red-top or serum gel tube. The specimen is refrigerated for up to 28 days, with a turnaround time of about 3 business days. Results are reported in micrograms per milliliter (mcg/mL), but they do not diagnose food allergies. Instead, they suggest sensitization, which may not correlate with allergic reactions. Physicians should order this test with an understanding of its limitations and interpret results within the broader clinical context.

Price of test:£68

The lowest price from the last 30 days: £68

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Grapefruit IgG test measures IgG antibodies specific to grapefruit in serum, indicating immunologic sensitization but not confirming a food allergy. Key points include:

- Clinical Utility: Used in specific cases for diet evaluation; not definitive for allergies.
- Procedure: Conducted via enzyme immunoassay; results standardized but not FDA-approved.
- Specimen Requirements: Serum from a red-top or serum gel tube; stored refrigerated.
- Turnaround Time: Typically 3 business days.
- Reporting: Results in mcg/mL; indicates sensitization, not allergy.

Understanding these aspects is vital for proper interpretation and clinical use.

Who Should Get Tested

The gastric parietal cell antibody (GPCA) test is crucial for diagnosing autoimmune conditions affecting the gastrointestinal system, particularly pernicious anemia. This blood test detects IgG antibodies against stomach parietal cells, essential for vitamin B12 absorption. Key points include:

- Purpose: Evaluates suspected pernicious anemia or vitamin B12 deficiencies.
- Procedure: Involves ELISA, serum separation, antigen binding, and spectrophotometric measurement.
- Interpretation: Results range from negative to positive, indicating antibody presence.
- Clinical Significance: Suggests pernicious anemia or other autoimmune diseases.
- Limitations: High sensitivity but not specific; requires clinical context for interpretation.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is essential for accurate clinical interpretation. The Grapefruit IgG test measures IgG antibodies specific to grapefruit, indicating immunologic sensitization but not confirming a food allergy. Key points include:

- Clinical Utility: Limited; not a definitive allergy diagnosis.
- Procedure: Enzyme immunoassay; standardized results.
- Specimen: Serum; stored refrigerated.
- Turnaround: 3 business days.
- Reporting: Results in mcg/mL; reference range starts at 2.0 mcg/mL.

Physicians should order this test understanding its limitations and interpret results within the broader clinical context.

Price of test:£68

The lowest price from the last 30 days: £68

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

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Language Model and Trusted Sources

At the core of Diagu's AI system is an advanced language model, engineered to transform complex medical data into clear, comprehensible, and informative descriptions. This model is adept at articulating detailed test analyses in a way that is accessible to both healthcare professionals and patients. The model's development involved the meticulous processing of high-quality sources, including reputable medical websites, renowned medical textbooks, and peer-reviewed research papers. This ensures that the language used in test descriptions is not only accurate and informative but also up-to-date with the latest medical findings and trends. By leveraging this rich tapestry of trusted sources, our AI system provides a deeper understanding of each test, fostering informed decision-making and enhanced patient care.

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