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HAV total
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.
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The test for HAV (Hepatitis A Virus) total antibodies is designed to detect the presence of both IgG and IgM antibodies specific to HAV antigens in the blood serum. This qualitative determination is useful in the serological diagnosis of Hepatitis A, helping to identify if an individual has been exposed to the virus or has developed immunity after vaccination or past infectio
Individuals who may have been exposed to Hepatitis A or those showing symptoms of the disease might need this test. It's also relevant for those who have traveled to areas with high prevalence of HAV or have come into close contact with an infected person. Additionally, the test can be used to determine if someone has developed immunity after vaccination or a past infection.
A positive result indicates the presence of HAV antibodies, suggesting either a past or recent exposure to the virus. It can also mean that the individual has been vaccinated against Hepatitis A. A negative result suggests that the person has not been exposed to the virus and might be at risk of contracting it. It's important to consult with a healthcare professional to interpret the results and determine the next steps.
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