HS- CRP

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The High Sensitivity C-reactive Protein (hs-CRP) assay is a blood test that measures the level of C-reactive protein (CRP) in the blood. CRP is a protein produced by the liver in response to inflammation, and high levels of CRP in the blood have been associated with an increased risk of cardiovascular disease (CVD). The hs-CRP assay is a more sensitive version of the standard CRP assay that can detect lower levels of CRP in the blood. The hs-CRP test is used to assess an individual's risk of developing CVD and to monitor the effectiveness of treatments for CVD. The test is simple and quick and involves a blood sample from an arm vein. Results are typically available within a few days and can be shared with patients via an online health portal or a physical copy upon request.

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The primary use of the hs-CRP test is to assess an individual's risk of developing cardiovascular disease (CVD). The test measures the level of C-reactive protein (CRP) in the blood, which is a marker of inflammation in the body. Inflammation is a key factor in the development of atherosclerosis, a condition in which plaque builds up in the arteries and can lead to heart attack or stroke. The hs-CRP test can detect low levels of CRP in the blood, making it a more sensitive indicator of inflammation than the standard CRP test.

The hs-CRP test may be recommended for individuals who have one or more risk factors for CVD, such as high blood pressure, high cholesterol, smoking, obesity, or a family history of heart disease. The test can help identify those who are at increased risk for CVD and may benefit from lifestyle changes or medication to lower their risk.

Other possible reasons for hs-CRP testing include

- Monitoring treatment for CVD: The hs-CRP test can be used to monitor the effectiveness of treatments for CVD, such as statins or other medications that reduce inflammation.
- Assessing overall health: In addition to its role in assessing CVD risk, the hs-CRP test can also be used as part of a general health assessment. Elevated CRP levels have been associated with other diseases such as rheumatoid arthritis and certain cancers.
- Prediction of future health outcomes: Studies have shown that elevated CRP levels are associated with an increased risk of other health problems besides CVD, including diabetes and some types of cancer.

Prevention is the key to managing cardiovascular disease and other health conditions. By identifying individuals at increased risk for these conditions through tests such as hs-CRP, healthcare providers can work with patients to develop personalized prevention plans that may include lifestyle changes such as diet and exercise or medication. Without early detection, individuals may be unaware of their risk and miss opportunities to prevent or manage these conditions.

The hs-CRP test is a valuable tool for assessing an individual's risk of developing cardiovascular disease and other health conditions. By detecting inflammation in the body, the test can help identify those who may benefit from lifestyle changes or medication to lower their risk. Early detection through testing can lead to better health outcomes and improved quality of life for patients.

Who Should Get Tested

The hs-CRP test may be recommended for individuals who have one or more risk factors for cardiovascular disease (CVD), such as

- high blood pressure
- high cholesterol
- Cigarette smoking
- Obesity
- Family history of heart disease

In addition, the hs-CRP test may be recommended for individuals who

- Have a personal history of heart attack or stroke
- Have diabetes
- Are over the age of 50
- Are postmenopausal women
- Have a chronic inflammatory disease such as rheumatoid arthritis or lupus

It is important to note that the hs-CRP test is not recommended for everyone. In some cases, the test may not provide useful information or may lead to unnecessary testing and treatment. Healthcare providers will consider an individual's overall health and risk factors when deciding whether to recommend the hs-CRP test.

Also keep in mind that while the hs-CRP test can help identify those at increased risk for CVD, it is not a definitive diagnostic tool. Other tests and evaluations may be needed to confirm a diagnosis or determine appropriate treatment.

Individuals who are concerned about their risk for CVD or who have one or more risk factors should talk to their healthcare provider about whether the hs-CRP test is right for them. By working with their healthcare provider, individuals can take steps to reduce their risk of developing CVD and improve their overall health.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

The hs-CRP test measures the level of C-reactive protein (CRP) in the blood, which is a marker of inflammation in the body. The results of the hs-CRP test can help healthcare providers assess an individual's risk for cardiovascular disease (CVD) and determine appropriate treatment.

The normal range for hs-CRP levels may vary depending on the laboratory performing the test.

In general, however, hs-CRP levels are interpreted as follows

- Low risk: Less than 1 mg/L
- Moderate risk: 1-3 mg/L
- High risk: Greater than 3 mg/L

It is important to note that hs-CRP levels can be affected by a number of factors, including infection, injury, and certain medications. Therefore, healthcare providers will consider an individual's overall health and other risk factors when interpreting hs-CRP results.

If an individual's hs-CRP level is elevated, his or her healthcare provider may recommend further testing or treatment to reduce the risk of CVD. This may include lifestyle changes such as diet and exercise, or medication to lower cholesterol or blood pressure.

For patients, it is important to discuss their hs-CRP results with their healthcare provider to fully understand what they mean for their health. By working with their healthcare provider, individuals can take steps to reduce their risk of CVD and improve their overall health.

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