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Insulin Resistance

Insulin Resistance

The Interleukin-6 (IL-6) lab test is a crucial diagnostic tool used to assess the body's inflammatory response by measuring IL-6 levels in the serum. Elevated IL-6 levels can indicate ongoing inflammation, often associated with systemic or localized infections, and chronic inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease. The test requires a serum sample, collected in a serum separator or plain red tube, and analyzed using an immunoenzymatic assay. This involves paramagnetic particles coated with anti-human IL-6 antibodies, with results determined via a chemiluminescent reaction. While IL-6 is a nonspecific marker, it provides valuable insights into inflammatory processes, aiding in the diagnosis and management of conditions such as sepsis and prosthetic joint infections. Additionally, IL-6 levels have been linked to COVID-19 severity, influencing treatment decisions. Despite its utility, IL-6 levels must be interpreted alongside other clinical findings due to potential diurnal variations and nonspecificity.

Price of test:£54

The lowest price from the last 30 days: £54

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The IL-6 lab test is essential for assessing inflammation in the body. It measures serum IL-6 levels to aid in diagnosing and managing conditions like rheumatoid arthritis and infections. Key points include:

- Purpose: Evaluates inflammatory response; elevated IL-6 suggests inflammation.
- Specimen: Requires serum, separated quickly, stored at -20°C if needed.
- Methodology: Uses immunoenzymatic assay with paramagnetic particles.
- Clinical Relevance: Indicates inflammation but not specific diseases.
- Interpretation: High IL-6 levels seen in infections and sepsis.
- COVID-19: Elevated IL-6 linked to severe cases.
- Treatment: Guides use of IL-6 inhibitors like tocilizumab.
- Limitations: Must be interpreted with clinical context.

Who Should Get Tested

Insulin resistance is a condition where the body's cells don't respond well to insulin, leading to high blood sugar levels. Testing for insulin resistance is crucial for early detection and management. Here's who should consider getting tested:

- Individuals with Excess Body Fat: Especially those with visceral fat around the belly.
- Sedentary Lifestyle: Lack of physical activity increases risk.
- Genetic Predisposition: Family history of diabetes or related conditions.
- Unhealthy Diet: High in refined carbs and low in fiber.
- Associated Conditions: Such as PCOS, heart disease, or metabolic syndrome.

Early detection helps prevent progression to more severe conditions.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results for the IL-6 lab test involves interpreting the levels of interleukin-6 in the serum to assess inflammation. Key points include:

- Elevated IL-6 Levels: Suggest an ongoing inflammatory response, potentially linked to infections or chronic inflammatory diseases.
- Normal IL-6 Levels: Do not rule out inflammation; clinical context is crucial.
- Diagnostic Use: Helpful in conditions like rheumatoid arthritis and COVID-19.
- Treatment Guidance: Elevated levels can influence treatment decisions, such as using tocilizumab for rheumatoid arthritis.
- Limitations: IL-6 is nonspecific; results should be considered alongside other clinical findings.

Price of test:£54

The lowest price from the last 30 days: £54

AI-Powered Insights and Expert Validation

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