Oestradiol
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The estradiol test also known as E2 test, measures the amount of estradiol, a primary estrogen hormone, in the blood. Estradiol plays a crucial role in reproductive functions and is produced mainly in the ovaries in women, the testes in men, and in smaller amounts by the adrenal glands, fat cells, and other tissues.
The estradiol test also known as E2 test, measures the amount of estradiol, a primary estrogen hormone, in the blood. Estradiol plays a crucial role in reproductive functions and is produced mainly in the ovaries in women, the testes in men, and in smaller amounts by the adrenal glands, fat cells, and other tissues.
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Purpose of the test
The primary purpose of the estradiol test is to gauge the levels of the hormone estradiol in the blood. In women, estradiol is essential for reproductive functions, including the growth of the womb, fallopian tubes, and vagina. In men, it helps prevent premature sperm death. The test can indicate the functionality of the ovaries, placenta, or adrenal glands, detect signs of an ovarian tumor, and monitor the response to fertility treatments.
Who Should Get Tested
The test is recommended for women who show signs of an ovarian tumor, whose periods have stopped, or to check the effectiveness of hormone therapy during menopause. It can also be used to monitor women undergoing fertility treatments. In men, it's used to determine if male or female body characteristics are developing normally.
Blood Test Preparation Guidelines
Time of day
It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
Drinking water prior to testing can help with sample collection.
Other factors
Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results
The results can vary based on gender and age. For men, the typical range is 10 to 50 pg/mL. For premenopausal women, it's 30 to 400 pg/mL, and for postmenopausal women, it's 0 to 30 pg/mL. Abnormal results can indicate various disorders, including early puberty in girls, gynecomastia in men, amenorrhea in women, and reduced ovarian function. The results can also highlight genetic issues like Klinefelter syndrome or Turner syndrome.
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