- Main page
- Tests catalogue
- Pistachio IgG
Pistachio IgG
The Proteinase 3 Antibodies (PR3 ANCA) test is a vital diagnostic tool for autoimmune vasculitis, especially Granulomatosis with Polyangiitis (GPA), formerly known as Wegener's granulomatosis. PR3 ANCA are specific antineutrophil cytoplasmic antibodies targeting the proteinase 3 antigen, a serine protease in neutrophils. In autoimmune conditions like GPA, the immune system erroneously attacks PR3, causing inflammation and organ damage, particularly in the kidneys and lungs. The presence of PR3 ANCA is highly specific for diagnosing active GPA, with about 90% of patients testing positive. However, a negative result does not entirely exclude the disease, as some patients with limited GPA may test negative. The test is also useful for monitoring disease activity and treatment response, as PR3 ANCA levels often correlate with disease activity. Typically performed using immunoassays, the test requires a serum sample and has a turnaround time of 2-4 days.
The Proteinase 3 Antibodies (PR3 ANCA) test is a vital diagnostic tool for autoimmune vasculitis, especially Granulomatosis with Polyangiitis (GPA), formerly known as Wegener's granulomatosis. PR3 ANCA are specific antineutrophil cytoplasmic antibodies targeting the proteinase 3 antigen, a serine protease in neutrophils. In autoimmune conditions like GPA, the immune system erroneously attacks PR3, causing inflammation and organ damage, particularly in the kidneys and lungs. The presence of PR3 ANCA is highly specific for diagnosing active GPA, with about 90% of patients testing positive. However, a negative result does not entirely exclude the disease, as some patients with limited GPA may test negative. The test is also useful for monitoring disease activity and treatment response, as PR3 ANCA levels often correlate with disease activity. Typically performed using immunoassays, the test requires a serum sample and has a turnaround time of 2-4 days.
The lowest price from the last 30 days: £34
Awaiting result:
One day
Collect material:
Blood
Prepare:
Proteinase 3 antibodies (PR3 ANCA) are crucial in diagnosing and monitoring autoimmune vasculitis, especially Granulomatosis with Polyangiitis (GPA). This test targets the proteinase 3 antigen, aiding in identifying active disease. Key points include:
- Clinical Significance: PR3 ANCA is highly specific for GPA, with 90% of active cases testing positive.
- Indications: Recommended for suspected vasculitis with kidney or lung symptoms.
- Interpretation:
- Negative: Usually no active GPA, but not definitive.
- Equivocal: Requires further testing.
- Positive: Indicates active GPA.
- Methodology: Uses immunoassays for detection.
- Monitoring: Tracks disease activity and treatment response.
The pistachio IgG test evaluates the immune response to pistachio nuts by measuring IgG antibodies in the blood. It is useful in diagnosing food sensitization and evaluating immunotherapy. The test involves:
- Blood Collection: A sample is drawn and placed in a serum gel or red-top tube.
- Serum Preparation: The sample is centrifuged, and serum is separated.
- Testing Method: ELISA or FEIA methods measure IgG levels.
- Interpretation: Results indicate sensitization but not necessarily an allergy.
Proper specimen handling ensures accurate results, aiding in effective treatment planning.
Understanding test results for the Proteinase 3 Antibodies (PR3 ANCA) test is crucial for diagnosing and monitoring autoimmune vasculitis, especially Granulomatosis with Polyangiitis (GPA). Here's a brief guide:
- Negative Result: Suggests no active GPA, but some cases may still test negative.
- Equivocal Result: Antibody levels between 2-3 IU/mL; further testing needed.
- Positive Result: Indicates active GPA, with levels above 3 IU/mL.
These results help differentiate GPA from other vasculitides and guide treatment decisions.
The lowest price from the last 30 days: £34
What is GetLabTest.com?
How do I get started with GetLabTest.com?
What diseases can GetLabTest.com detect?
How do I prepare for testing with GetLabTest.com?
Can I speak with a doctor about my results?
Is testing with GetLabTest.com covered by insurance?
How long does it take to receive the test results?
Can I access my test results online?
Is my personal information kept confidential?
What if I have questions or concerns about my test results?