The serum Cytomegalovirus (CMV) Polymerase Chain Reaction (PCR) test is a vital diagnostic tool for detecting and quantifying CMV DNA in serum or plasma. It plays a crucial role in diagnosing active CMV infections, monitoring disease progression, and evaluating the effectiveness of antiviral treatments. CMV, a common virus from the herpes family, often remains dormant after initial infection but can reactivate, posing significant risks to individuals with weakened immune systems, such as those with HIV/AIDS, organ transplant recipients, and pregnant women. The test involves collecting a blood sample, processing it to extract CMV DNA, and using real-time quantitative PCR to detect and measure the viral load. Results guide clinical decisions, with interpretations ranging from undetected to high-level infections. The test's clinical utility is significant in managing CMV-related health risks, particularly in vulnerable populations, by enabling early detection and timely intervention to prevent severe complications.
The serum Cytomegalovirus (CMV) Polymerase Chain Reaction (PCR) test is a vital diagnostic tool for detecting and quantifying CMV DNA in serum or plasma. It plays a crucial role in diagnosing active CMV infections, monitoring disease progression, and evaluating the effectiveness of antiviral treatments. CMV, a common virus from the herpes family, often remains dormant after initial infection but can reactivate, posing significant risks to individuals with weakened immune systems, such as those with HIV/AIDS, organ transplant recipients, and pregnant women. The test involves collecting a blood sample, processing it to extract CMV DNA, and using real-time quantitative PCR to detect and measure the viral load. Results guide clinical decisions, with interpretations ranging from undetected to high-level infections. The test's clinical utility is significant in managing CMV-related health risks, particularly in vulnerable populations, by enabling early detection and timely intervention to prevent severe complications.
The lowest price from the last 30 days: £34
Awaiting result:
One day
Collect material:
Blood
Prepare:
The serum CMV PCR test is pivotal in diagnosing and managing CMV infections. It detects and quantifies CMV DNA in serum, crucial for:
- Diagnosing active infections
- Monitoring disease progression
- Assessing antiviral therapy effectiveness
Specimen Collection:
- Blood drawn from a vein
- Serum separated via centrifugation
- Stored at 2 to 8°C or frozen at -20°C
Methodology:
- DNA extraction and amplification
- Real-time detection with fluorescent probes
Interpretation:
- Undetected: No current infection
- <35 IU/mL: Low-level infection
- >10,000,000 IU/mL: High-level infection
This test is essential for transplant patients, pregnant women, and immunocompromised individuals.
The Clam IgG test is a diagnostic tool used to assess immunologic sensitization to clam allergens. It is particularly useful in evaluating food-related complaints or suspected food allergies. However, the presence of IgG antibodies does not confirm a food allergy. Physicians should order this test, understanding its limitations and interpreting results appropriately. Key considerations include:
- Specimen Requirements: Serum sample, preferably 0.5 mL, refrigerated for stability.
- Turnaround Time: 2 to 4 business days.
- Interpretation: Values <2.0 mcg/mL indicate absent allergen-specific IgG antibodies. Higher values suggest sensitization.
This test should be used alongside other diagnostic tools for comprehensive evaluation.
Understanding test results is crucial for managing CMV infections effectively. The serum CMV PCR test detects and quantifies CMV DNA, providing insights into infection status. Key interpretations include:
- Undetected: No CMV DNA, suggesting no current infection.
- <35 IU/mL: Low-level infection or reactivation, with limited quantification.
- >10,000,000 IU/mL: High-level infection, indicating severe reactivation.
Quantitative values in IU/mL and log IU/mL help monitor disease progression and treatment response. Changes over 0.5 log IU/mL are significant, guiding clinical decisions for transplant patients, pregnant women, and immunocompromised individuals.
The lowest price from the last 30 days: £34
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