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  3. Serum Cholinesterase (pseudo)

Serum Cholinesterase (pseudo)

The Sesame Seed IgE test is a vital diagnostic tool used to identify allergies to sesame seeds by detecting specific IgE antibodies in the blood. This test is crucial for diagnosing sesame allergies, which are increasingly common and can lead to severe allergic reactions. It employs the Fluorescence Enzyme Immunoassay (FEIA) method to measure IgE levels, providing insights into the patient's sensitization to sesame seeds. The test involves collecting a blood sample, testing it for IgE antibodies using an ImmunoCAP system, and interpreting the results based on IgE levels. A positive result indicates an allergic reaction to sesame seeds. The test also helps identify cross-reactivity with other allergens like peanuts and tree nuts, aiding in comprehensive allergy management. While the test is invaluable for diagnosis and management, it has limitations, such as potential false positives and the need for clinical context in interpreting results. Overall, it plays a crucial role in allergy diagnosis and management.

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Price of test:£68

The lowest price from the last 30 days: £68

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Awaiting result:

One day

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Collect material:

Blood

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Prepare:

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Purpose of the test

The Sesame Seed IgE test is a vital diagnostic tool for identifying sesame allergies by detecting specific IgE antibodies in the blood. It serves several purposes:

- Diagnosis: Confirms sesame allergy, crucial as such allergies are increasingly common and can be severe.
- Cross-Reactivity: Identifies potential cross-reactivity with other allergens like peanuts and tree nuts.
- Management Plan: Guides treatment strategies based on sensitivity levels.
- Oral Food Challenge: Assists in determining the need for supervised food challenges.

Despite its utility, the test has limitations, including potential false positives and the need for clinical context.

Who Should Get Tested

Serum cholinesterase testing is essential for specific individuals:

- Agricultural Workers: Those exposed to organophosphate pesticides need monitoring to prevent nerve overstimulation.
- Surgical Patients: Preoperative evaluation is crucial for patients receiving succinylcholine to avoid prolonged apnea.
- Genetic Screening: Approximately 3% of the population has a pseudocholinesterase deficiency, necessitating alternative anesthetics.
- Liver Disease Patients: Decreased enzyme levels may indicate liver issues, aiding in diagnosis.

Understanding these needs ensures effective diagnosis and management, safeguarding patient health and safety.

Blood Test Preparation Guidelines
Time of day
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It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.
Fasting
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It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.
Stay hydrated
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Drinking water prior to testing can help with sample collection.
Other factors
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Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.
Medications and supplements:
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Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.
Biotin supplements:
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High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.
Interpreting Test Results

Understanding test results is crucial for managing sesame allergies effectively. Here's a concise guide:

- Positive Result: Indicates the presence of IgE antibodies against sesame seeds, suggesting an allergy.
- IgE Levels: Higher levels correlate with increased likelihood of allergic reactions.
- Component Testing: Identifies specific proteins like Ses i 1, crucial for assessing reaction severity.
- Cross-Reactivity: Helps identify potential allergies to related foods like peanuts.
- Management: Guides dietary adjustments and potential oral food challenges.
- Limitations: Consider clinical history and potential false positives for accurate diagnosis.

Price of test:£68

The lowest price from the last 30 days: £68

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