Sex Hormone Binding Globulin

The SHBG test is indicated for individuals who are experiencing symptoms related to sex hormone imbalances or who are at risk for developing conditions related to these imbalances. Some specific groups of people who may benefit from the SHBG test include

- Women with irregular periods, acne, weight gain, or excessive hair growth: These symptoms may indicate polycystic ovary syndrome (PCOS), which can be diagnosed with an SHBG test.
- Men with low libido, fatigue, or muscle weakness: These symptoms may indicate hypogonadism, which can be diagnosed using an SHBG test in conjunction with total testosterone levels.
- Women with excessive hair growth: This symptom may indicate hirsutism, which can be evaluated using an SHBG test in conjunction with sex hormone levels.
- Individuals at risk for osteoporosis: Low levels of sex hormones such as testosterone and estrogen can increase the risk of osteoporosis. An SHBG test can help evaluate these hormone levels and assess risk for osteoporosis.
- Individuals at risk for cardiovascular disease: High levels of sex hormones such as testosterone and estrogen have been linked to an increased risk of cardiovascular disease. An SHBG test can help evaluate these hormone levels and assess risk for cardiovascular disease.

However, it's important to note that the decision to order an SHBG test should always be made by a qualified healthcare provider based on a patient's individual needs and medical history.

Interpreting SHBG test results is an important part of diagnosing and managing conditions related to sex hormone imbalances. Here are some general guidelines for interpreting SHBG test results:

- Normal range: The normal range for SHBG levels varies depending on age, gender, and other factors. In general, normal SHBG levels are higher in women than in men.
- High SHBG levels: High SHBG levels may indicate that less free testosterone is available to the body's tissues than is indicated by a total testosterone test. This can be caused by a number of factors, including aging, liver disease, hyperthyroidism, or certain medications such as birth control pills or anti-androgens.
- Low SHBG levels: Low SHBG levels may indicate that more free testosterone is available to the body's tissues than is indicated by a total testosterone test. This can be caused by a number of factors, including obesity, insulin resistance, hypothyroidism, or certain medications such as steroids or progestins.

What's important to note is that interpreting SHBG test results requires careful consideration of other factors, such as total testosterone levels and clinical signs and symptoms. Your healthcare provider will use these results in conjunction with other diagnostic tests and your medical history to develop an appropriate treatment plan, if needed.

In conclusion, interpretation of SHBG test results should be made by a qualified healthcare provider who is able to consider all relevant factors. High or low SHBG levels may indicate underlying health conditions that require further evaluation and treatment.