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Sickle Cell Screen

Sickle Cell Screen

The Silver Birch IgE test is a vital diagnostic tool used to detect specific IgE antibodies in the blood, indicating an allergic reaction to silver birch (Betula verrucosa). This test is essential for diagnosing silver birch allergies and identifying the allergen responsible for symptoms such as respiratory issues, skin rashes, or gastrointestinal problems following exposure to birch pollen. Utilizing the Fluorescent Enzyme Immunoassay (FEIA) method, the test ensures high accuracy by minimizing non-specific binding. A blood sample is analyzed, and IgE levels are classified from Class 0 (undetectable) to Class 6 (very high positive), reflecting the severity of the allergic response. Clinically, the test aids in diagnosing allergies, confirming sensitization before immunotherapy, and investigating allergic reactions to other allergens. While highly accurate, results should be interpreted in the clinical context, considering potential false positives in patients with elevated serum IgE levels. The test typically has a turnaround time of 2-4 days.

Price of test:£68

The lowest price from the last 30 days: £68

Awaiting result:

One day

Collect material:

Blood

Prepare:

Learn more

Purpose of the test

The Silver Birch IgE test is a vital diagnostic tool for identifying allergies to silver birch. It measures specific IgE antibodies in the blood, indicating an allergic reaction. The test is essential for diagnosing silver birch allergies and determining the allergen causing symptoms.

- Purpose: Identifies allergic responses, confirms sensitization before immunotherapy.
- Methodology: Uses ImmunoCAP FEIA, involving serum collection and analysis.
- Result Interpretation: Ranges from Class 0 (undetectable) to Class 6 (very severe).
- Clinical Utility: Diagnoses allergies, defines allergen specificity, confirms sensitization.
- Considerations: False positives possible; interpret results in clinical context.

Who Should Get Tested

The sickle cell screen is vital for identifying sickle cell disease (SCD) or trait, aiding early management. Key groups for testing include:

- Newborns: Routine screening ensures early detection.
- Immigrants: Testing is crucial for those untested in their home countries.
- Children Moving: Screening is advised for children relocating to new areas.
- Symptomatic Individuals: Anyone showing symptoms should be tested.
- Family History: Those with a family history of SCD or trait should consider testing.

Early diagnosis allows for timely treatment, improving health outcomes and quality of life.

Blood Test Preparation Guidelines

Time of day

It is recommended to schedule your appointment for blood tests in the morning hours between 7:00-10:00.

Fasting

It is recommended to fast for approximately 12 hours before blood sampling. The last meal of the previous day should ideally be consumed around 6:00 p.m. On the day before the test, avoid heavy and fatty meals as well as alcohol.

Stay hydrated

Drinking water prior to testing can help with sample collection.

Other factors

Tests should not be performed after a sleepless night or intense physical activity. It is recommended to avoid exercise and stress immediately before blood collection and to not smoke. A short rest is recommended.

Medications and supplements:

Blood samples should be collected before the morning dose. Some drugs can interfere with test results. Consult with your doctor whether you can delay your dose because of lab tests.

Biotin supplements:

High doses of biotin supplements can affect test results, causing false elevation or reduction. It's recommended to avoid taking biotin for at least 72 hours before blood collection. If you are taking biotin, inform the personnel collecting the blood so that they can provide specific instructions.

Interpreting Test Results

Understanding test results is essential for managing allergies effectively. The Silver Birch IgE test identifies specific IgE antibodies, indicating an allergic response to silver birch. Here's a brief overview:

- Class 0: No allergic response.
- Class 0/1: Possible sensitization.
- Class 1: Mild reaction.
- Class 2: Moderate reaction.
- Class 3: Significant reaction.
- Class 4: Severe reaction.
- Class 5/6: Very severe reaction.

This test aids in diagnosing allergies, defining allergen specificity, and confirming sensitization before immunotherapy. Always consider clinical context and potential false positives.

Price of test:£68

The lowest price from the last 30 days: £68

AI-Powered Insights and Expert Validation

Advanced AI Interpretation

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