The Vitamin B2 (Riboflavin) lab test is essential for assessing riboflavin levels in blood plasma, crucial for diagnosing and monitoring deficiencies. Riboflavin, a vital B vitamin, supports energy production, enzyme function, and antioxidant synthesis. Due to its water-soluble nature, it requires a constant dietary supply, as the body does not store it in significant amounts. Clinically, the test is used to evaluate symptoms of riboflavin deficiency, such as ariboflavinosis, which includes sore throat, lip lesions, and anemia, as well as subtle deficiencies that impair energy production and increase oxidative stress. The test involves collecting a blood sample, preferably plasma heparin, and analyzing it using liquid chromatography tandem mass spectrometry (LC-MS/MS) for accurate results. Normal plasma levels range from 1-19 mcg/L, with low levels indicating potential deficiency. The test's turnaround time is typically 1-6 days, providing critical insights for healthcare providers to manage and treat riboflavin deficiency effectively.
The Vitamin B2 (Riboflavin) lab test is essential for assessing riboflavin levels in blood plasma, crucial for diagnosing and monitoring deficiencies. Riboflavin, a vital B vitamin, supports energy production, enzyme function, and antioxidant synthesis. Due to its water-soluble nature, it requires a constant dietary supply, as the body does not store it in significant amounts. Clinically, the test is used to evaluate symptoms of riboflavin deficiency, such as ariboflavinosis, which includes sore throat, lip lesions, and anemia, as well as subtle deficiencies that impair energy production and increase oxidative stress. The test involves collecting a blood sample, preferably plasma heparin, and analyzing it using liquid chromatography tandem mass spectrometry (LC-MS/MS) for accurate results. Normal plasma levels range from 1-19 mcg/L, with low levels indicating potential deficiency. The test's turnaround time is typically 1-6 days, providing critical insights for healthcare providers to manage and treat riboflavin deficiency effectively.
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Vitamin B2, or riboflavin, is essential for energy production and enzyme function. The Vitamin B2 lab test measures riboflavin levels in blood plasma to diagnose deficiencies. Key points include:
- Clinical Uses: Identifies riboflavin deficiency, which can cause symptoms like sore throat, lesions, and anemia.
- Test Procedure: Involves a blood sample, preferably fasting, using plasma heparin.
- Specimen Requirements: Amber vial, 2 mL plasma, light-protected.
- Methodology: LC-MS/MS for accurate measurement.
- Interpretation: Low levels indicate deficiency; normal levels suggest other causes.
The Vitamin B2 test is essential for diagnosing riboflavin deficiencies, which can manifest in various ways. Individuals who should be tested include those with:
- Symptoms of ariboflavinosis, such as sore throat and lesions on the lips.
- Subtle deficiencies affecting energy production and enzyme activity.
- Inborn errors of metabolism with neurodegenerative features.
The test involves a blood sample analyzed using LC-MS/MS, with results indicating deficiency or normal levels. Accurate diagnosis aids in managing health issues related to riboflavin deficiency.
Understanding test results for Vitamin B2 is essential for diagnosing and managing deficiencies. Here's a brief guide:
- Low Levels: May indicate deficiency; consider factors like supply, absorption, or utilization.
- Normal Levels: Suggest symptoms might have other causes.
- High Levels: Rare, usually due to excessive supplementation.
Ensure accurate results by following preparation guidelines, such as fasting. The test's turnaround time is typically 1-6 days, allowing for timely clinical decisions. Understanding these results aids in effective healthcare management.
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