The Whey IgG test is a laboratory assay designed to measure immunoglobulin G (IgG) antibodies specific to whey proteins in a patient's serum. IgG antibodies play a role in the immune system, and their presence can indicate immunologic sensitization to whey proteins, commonly found in dairy products. However, the presence of IgG antibodies alone does not confirm a food allergy, which is typically associated with IgE antibodies. The test is performed using an enzyme immunoassay (EIA) and requires a serum specimen. Results are expressed in micrograms per milliliter (mcg/mL), with a typical turnaround time of 3 business days. While high IgG levels may suggest sensitization, they do not necessarily indicate an allergy, as IgG4, a subclass of IgG, is often associated with tolerance. The test has limitations and is not FDA-approved for diagnostic use. It should be interpreted within a broader clinical context and alongside other diagnostic methods.
The Whey IgG test is a laboratory assay designed to measure immunoglobulin G (IgG) antibodies specific to whey proteins in a patient's serum. IgG antibodies play a role in the immune system, and their presence can indicate immunologic sensitization to whey proteins, commonly found in dairy products. However, the presence of IgG antibodies alone does not confirm a food allergy, which is typically associated with IgE antibodies. The test is performed using an enzyme immunoassay (EIA) and requires a serum specimen. Results are expressed in micrograms per milliliter (mcg/mL), with a typical turnaround time of 3 business days. While high IgG levels may suggest sensitization, they do not necessarily indicate an allergy, as IgG4, a subclass of IgG, is often associated with tolerance. The test has limitations and is not FDA-approved for diagnostic use. It should be interpreted within a broader clinical context and alongside other diagnostic methods.
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The Whey IgG test is a laboratory assay designed to measure IgG antibodies specific to whey proteins in serum. Its clinical utility includes identifying potential adverse reactions to whey, though it doesn't confirm food allergies, which are linked to IgE antibodies. Key points include:
- Procedure: Uses enzyme immunoassay for IgG concentration.
- Specimen: Requires 0.5 mL serum, refrigerated or frozen.
- Turnaround: Typically 3 business days.
- Interpretation: Results in mcg/mL; high IgG suggests sensitization, not allergy.
- Limitations: Not FDA-approved; not sole diagnostic tool.
The Whey IgE test is essential for diagnosing whey allergies, commonly found in dairy products like cow's milk. It identifies IgE antibodies, indicating an allergic reaction. Symptoms can range from mild, such as hives and itching, to severe, like anaphylaxis. The test uses a Fluorescence Enzyme Immunoassay (FEIA) method, involving:
- Sample collection
- Allergen coupling
- Incubation and washing
- Enzyme labeling
- Fluorescence measurement
Results guide allergy management, confirming sensitization and aiding treatment decisions. Proper specimen handling ensures accuracy, making this test crucial in allergy diagnosis.
Understanding test results is crucial for making informed health decisions. Here’s a brief guide to interpreting Whey IgG test outcomes:
- Result Expression: Measured in micrograms per milliliter (mcg/mL).
- Quantitation Limits:
- Lower Limit: 2.0 mcg/mL (undetectable below this).
- Upper Limit: 200 mcg/mL (maximum measurable concentration).
- Clinical Context: High IgG levels suggest sensitization but not necessarily an allergy.
- Limitations: Not FDA-approved for diagnostics; should not solely guide dietary changes.
- Considerations: Use alongside other tests like IgE for comprehensive allergy assessment.
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