A serum folate test is a blood test that assesses the concentration of folate (vitamin B9) in the blood. Folate plays a crucial role in many bodily functions, including:
- Red blood cell production: Folate is essential for the formation of healthy red blood cells. A deficiency can lead to megaloblastic anemia, characterized by abnormally large and poorly functioning red blood cells.
- DNA synthesis and repair: Folate is necessary for the synthesis and repair of DNA, making it essential for cell division and tissue growth, particularly during periods of rapid growth like pregnancy.
- Neurological health: Folate is also important for maintaining neurological health, and a deficiency can lead to cognitive difficulties, confusion, or memory problems.
When is it needed?
- Suspected folate deficiency: A serum folate test is recommended if there are symptoms such as fatigue, weakness, or unexplained anemia. Folate deficiency can cause megaloblastic anemia, a type of anemia that affects red blood cell production.
- Pregnancy: Folate is essential for the development of the fetal neural tube. Insufficient levels during pregnancy can lead to neural tube defects, so folate levels are often monitored.
- Malabsorption disorders: Conditions like celiac disease or Crohn’s disease, which affect nutrient absorption, may also necessitate this test to ensure the body is absorbing sufficient folate.
Recommended Tests:
- Vitamin B12 (Active B12): Vitamin B12 is often tested alongside folate, as deficiencies in both can lead to similar symptoms like anemia and neurological issues.
Active B12 Test - Complete Blood Count (CBC): A CBC is frequently recommended with a serum folate test to evaluate overall blood health and detect anemia or abnormal red blood cell production.
Complete Blood Count (CBC)
